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Valley Vet Supply distributed unapproved antimicrobial drugs including amoxicillin, ciprofloxacin, doxycycline, and other antibiotics marketed for use in aquarium fish and birds without FDA approval or compliance with drug listing and facility registration requirements. The products violated the Federal Food, Drug, and Cosmetic Act because they were misbranded new animal drugs introduced into interstate commerce without being drug-listed with FDA or manufactured in an FDA-registered facility. Website claims describing the products as treatments for bacterial infections in fish established them as drugs rather than unapproved dietary supplements or other non-drug categories.