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Based on limited metadata, the FDA issued a Warning Letter to Hangzhou Zhongbo Industrial Co., Ltd., a drug manufacturer, on November 27, 2018. Without access to the full letter text or specific subject line, the exact nature of the violations cannot be determined from the available information. The letter falls under FDA's drug product regulatory jurisdiction, though the specific issuing office is not identified in the metadata provided. Additional details about the manufacturing, quality control, or compliance issues would require review of the complete Warning Letter.